Sentence examples for unique determinant from inspiring English sources

This indicates that binding of the enzyme to its substrate is not the unique determinant for an efficient recombination but that proficient synaptic complex formation, mediated by the correct folding and oligomerization of the protein on the substrates, could be the limiting step of the process.

In Paramecium, it has been shown that gene expression level is a major (but not the unique) determinant of gene retention after polyploidization [ 18], using the same P. tetraurelia microarray resource described here.

Noteworthy, the knockdown of A3G in unstimulated CD4+ T cells does not turn them permissive to infection, suggesting that the presence of LMM A3G in the cells is not the unique determinant for their resistance to HIV-1 [ 62, 63].

Researchers have shown that age of onset may not necessarily act as a unique determinant in the course of schizophrenic disorder as evidence indicates that men have an earlier age of illness onset than women [ 3- 6] and a more severe course of illness, particularly in the short and medium terms [ 41].

On the other hand, one study of 112 patients who underwent total knee replacement (TKR) [ 19] examined which was the most important unique determinant of global outcome/satisfaction after surgical management: baseline expectations, fulfillment of expectations or current symptoms and function.

Patient's expectations are variably reported to influence self-rated outcome and satisfaction after medical treatment; this prospective study examined which of the following was the most important unique determinant of global outcome/satisfaction after total knee arthroplasty (TKA): baseline expectations; fulfilment of expectations; or current symptoms and function.

These findings suggest that there are heterogeneous trajectories of disaster-related PTSD symptoms in older adults and that these trajectories have common and unique determinants.

Such programs should be grounded in behaviour change theory, and address the unique determinants of PA adoption and maintenance in the post-treatment breast cancer population [ 30, 31].

We evaluated home characteristics as predictors of multiple microbial biomarkers, with a focus on common and unique determinants and with attention to the extent of their explanatory ability.

Interventions designed to reduce incidents of absconding must therefore understand the multiple and often unique determinants for this behavior among forensic populations, and the need for individualized risk formulation and management.

Although a number of HDAC inhibitors are being evaluated in preclinical cancer models and in clinical trials, little is known about the differences in their specific mechanism of action and about the unique determinants of cancer cell sensitivity to each of these inhibitors.