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A conformer is then defined as a unique conformation represented as a set of integer numbers, one for each dihedral bond, identifying the bin.
We assume that CaM undergoes a conformational transition upon Ca2+ binding and adopts a unique conformation according to the number of bound ions.
Mannose in the −1 subsite hydrogen bonded with His113 and Tyr131, revealing a unique conformation.
Phosphorylated phospholamban stabilizes a unique conformation of SERCA that is characterized by a compact architecture.
However, it is difficult to determine the unique conformation of flexible linkers due to many local minima in free energy.
The ΔPhe-Trp is a newly designed moiety that was found inducing a unique conformation in peptides.
The unique conformation of polymeric chain is a consequence of rotation of the atoms or atom groups around a single bond.
Comparison to other DHPS structures reveals that the M. tuberculosis DHPS structure is in a unique conformation in which loop 1 closes over the active site.
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These two unique conformations illustrate the active site conformational rearrangements that occur as the complex proceeds from the step 2 product, immediately following step 2 chemistry, to the step 3 substrate, immediately preceding step 3 chemistry.
Conformational analysis indicated that the lower the number of unique conformations accessible by an inhibitor, the greater the biological activity displayed by the compound against LnCAP cells.
This could be ascribed to the unique conformations of CMCs.
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