L. pneumophila replicates vigorously within this unique compartment, evading lysosomal fusion [5].
The Voronoi partitioning ensures that each cell-graph edge resides in a unique compartment as depicted in Figure 3(b).
This vacuole represents a unique compartment, shielding the parasite from the host cell cytosol, but nevertheless allowing passage of nutrients, waste products and even large polypeptides both to, and from the host cell and surrounding environment [1].
When engulfed by macrophages, serovar Typhimurium produces a series of virulence factors that allow the bacterium to inhibit the delivery of the antibacterial substances to the phagosome, to survive the various killing mechanisms, and to propagate in a unique compartment called the Salmonella containing vacuole [7].
This unique compartment is the bone marrow.
In the ovary, oocytes differentiated and proceeded to meiosis up to the early diplotene stage in a unique compartment of the ovary called the 'germinal cradle', which might be similar to the cyst compartments in the testes where spermatogenic cells are differentiating synchronously.
However, none of the markers for Marinesco bodies (HDAC6), the perinuclear compartment (CUG-BP1, PML, HSF1 and CD99), clastosomes (proteasomal subunits PSMC2 and PSMC4) and nucleolar caps (fibrillarin, coilin and PML) colocalized with para-nucleolar DPR inclusions, indicating they represent a unique compartment.
40 In a bone marrow transplant patient who was shown to be totally rid of the virus, only the bone marrow was changed to confer resistance to re-infection, even in the presence of other target cells in the general circulation, suggesting bone marrow is indeed a different and unique compartment in the process of HIV infection.
This correlates with reports that the rapid secretion of CCL5 from memory and effector CD8+ T cells is from stored granules, which are thought to be a unique compartment, distinct from lysosomal secretory granules, and that this secretion is resistant to ER and Golgi blockade [ 36, 37, 40].
Plasmodium parasites contain several unique membrane compartments in which prenylated proteins may play important roles in pathogenesis.
