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This yielded unique assignments for 94.1% (606 of 644) of the NOE peaks observed, providing 488 nonredundant H H distance constraints.
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In ideal cases, this procedure can be automated and yields a unique assignment for each backbone atom of the protein (see, Baran et al., 2004; Moseley and Montelione, 1999 for review).
First, the high cross-correlation (CC) values from the docking calculations are not by themselves evidence of a unique assignment – for example, what was the CC when the HEAT repeats were fit in the pink density rather than the blue density?
Despite the low percentage of unique assignments (30%) for EIN, the SAR concept leads to useful results for the localization of the interaction site with Hpr (Fig. 5).
We found that the use of sparse or poorly constraining NMR data for the structure-based assignment cannot lead to a unique assignment of all peaks.
Look for unique assignments.
This enables the use of efficient propagators for most of the required constraints, such as the algorithm of Regin [ 36] for globally unique assignments.
Davis was a 27-year-old fine arts major, still mourning the death of an older brother in an auto accident a month earlier, when the professors Daniel Livingston and Craig Wedderspoon presented a unique assignment to him: draft a model for a statue of one of college football's iconic active coaches.
A unique assignment is possible if only one SVM produces a positive output for a certain sample.
The authors assumed the existence of an algorithm that can determine, for any distribution of users of various classes in various regions, whether there is a feasible power assignment satisfying the signal-to-noise requirements for all users and, if so, provide a unique power assignment for the distribution.
Quality control preprocessing of SNPs was performed by eliminating SNPs that did not match the following criteria: (i) less than 10% missing values, (ii) minor allele frequency of greater than 2.5%, (iii) no more than three heterozygous genotypes, and (iv) unique allele assignment for the 22 replicated checks of genotype B73.
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