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The recent implementation of the "Munich method" alongside the SiFA-IE labeling approach for peptide and protein labeling [ 43, 46, 58, 59] offers unique and unequalled simplicity, where, starting from commercially available [F]F−/[O]H2O, it is possible to deliver [F]SiFA radiopharmaceuticals using only room temperature transformations and facile cartridge-based manipulations.
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