Sentence examples for unique alignments from inspiring English sources

For gene expression analysis, we only examined transcripts with a reciprocal hit in the other genotype where >75% of the aligned reads were unique alignments, not aligning to any other transcripts.

We show ∼1.5% gain in unique alignments shown if mismatch tolerant aligner settings are used, although a more substantial difference could be seen when perfect matches were required.

Within each sample, an average of 5.5 M of these reads were unique alignments, while an average of 13.9 M mapped reads also aligned to other transcripts.

Sequences from approximately 144 million 100 bp paired-end reads were quality-filtered and mapped to the Trichoderma reesei 2.0 reference genome, (http://genome.jgi-psf.org/Trire2/Trire2.home.html) using the Bowtie aligner version 0.12.8 [ 35] allowing two mismatches and only unique alignments.

To determine the most likely genomic source of sequences aligning antisense within the 3' UTR clusters, these sequences were extracted and re-aligned to the genome under strict conditions (up to one mismatch, unique alignments only).

These sequences were quality-filtered and mapped to the Trichoderma reesei 2.0 reference genome, available from the JGI Genome Portal (http://genome.jgi-psf.org/Trire2/Trire2.home.html), using the Bowtie aligner version 0.12.8 [ 54], allowing for two mismatches and only unique alignments.

Each aligned read was assigned a mapping quality that indicates whether the read has a unique alignment or can be aligned to multiple positions in the genome [ 22].

On average, 36 million uniquely aligned reads were obtained per data set, representing an average unique alignment rate of 76%.

We then aligned the Illumina reads to the D. melanogaster exome, requiring unique alignment to a single location and allowing one, two, or three mismatches.

Andrew Simms of the New Economics Foundation said: "We face a unique alignment of economic and environmental interests.

This unique alignment, Gates and McConnell believed, would offer the best chance that the intelligence community would ever have to reform itself.