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CoC means that the probability of escape from containment, dissemination and unintended interaction with the environment must be virtually zero.
At the sequence level, comparison with the human (host) proteome can be useful in filtering out those targets that have detectable homologues in the human cells, in order to reduce the risk of adverse effects that arise due to unintended interaction of the drug with the host protein.
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Both methods deploy different constellations of intended and unintended interactions between visual appearance and underlying biological materiality.
We'd also like to point out that these unintended interactions pose serious problems for an often overlooked segment of our society the working poor.
Forbes magazine's recent cover story "When Work Doesn't Pay For the Middle Class" illustrates many of the issues the middle class faces regarding the unintended interactions between work, marriage and taxes.
In addition to the necessity for accuracy and robustness that both serve as prerequisites for the successful performance of various tasks, the ability to safely handle unexpected events, such as communication failures or unintended interactions which may endanger the robot/human safety, is a paramount requirement.
A qualitative relationship between promoter parts and regulatory proteins will allow us to query and infer intended and unintended interactions.
The particle of interest was easily maneuvered in a dense field of other pathogens without additional unintended interactions of the trap with other particles.
This work also calls for careful chemical and biological characterization of leads obtained from HTSs to avoid identification of irrelevant chemical structures and interference caused by unintended interactions with luciferase.
To that end, it is important to check for known unintended interactions between analytes and sorbents.
In addition, the simultaneous ablation of multiple points may lead to unintended interactions between multiple cavitation bubbles in the tissue confounding interpretations of the post-ablation tissue movements.
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CEO of Professional Science Editing for Scientists @ prosciediting.com