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It urged developers to check their source code for unintended changes.
These are familiar stories of big companies recalling products because of new – unintended – changes to the recipe.
Kuzma is particularly concerned about unforeseen changes to DNA that occur because tools such as CRISPR aren't perfect and may make unintended changes to other genes.
This technique has been used for decades and is not regulated, even though it can potentially cause unknown and unintended changes to crops.
They include the application of technologies such as proteomics and metabolomics to assess unintended changes, and the development of predictive methods to evaluate allergenicity.
Unintended changes of the thickness of the coating, e.g. caused by variation of the web speed, were found to preclude the correct analysis of the conversion by chemometric methods.
Research to date has not comprehensively addressed genome-editing specificity and off-target mismatches that may result in unintended changes within plant genomes or the potential for gene drive initiation.
Because of the importance of platen emissivity to the thermal environment of the wafers, users should be aware of unintended changes in emissivity as platens become coated through weeks or months of use.
Unintended changes brought about by human activities are even more widespread and include forest clearance, agriculture, grazing, road construction, and urbanization, which increase rates of rainfall runoff and accelerate processes of water erosion.
The committee also argued that technologies for analyzing a plant's DNA, as well as the molecules and proteins produced in its cells, can be used to test new varieties for unintended changes and determine whether the crops pose new risks compared with their nonengineered counterparts.
A checksum is a short extra piece of data kept in addition to the file itself which is the sum (or some other simple function) of all values in the file that is used to detect unintended changes to a program (e.g. when another program accidentally overwrites it).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com