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There were minor and clinically unimportant differences in IGFBP-1 during the later part of the study (6 9 h) between insulin aspart and RHI.
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Only if the two occupations differ on important characteristics will they be measured as "far away" by this measure, whereas unimportant differences could result in an overstatement of the distance as measured in number 1. Consequently this paper employs the second (importance weights) calculation of distance between occupations.
Seemingly unimportant differences between two situations or systems can translate into major differences in outcomes.
In both studies at baseline, there was no evidence of any differences in the overall or domain scores except for the activity limitation and environmental stimuli domains in study 1, where small but clinically unimportant differences were observed (the minimal important difference for the AQLQ is 0.5 on the 7-point scale [ 12]).
Perhaps the commentators themselves misunderstand the study and think it found only practically unimportant differences.
It would be inappropriate to power a study to detect a small, clinically unimportant difference.
Shared environmental effects were unimportant in explaining individual differences in impulsivity.
Until the middle of the 1980s, for me and for others I was in contact with who had different ethnic backgrounds, the identity and differentiation of "nationality" (minzu) seemed unimportant; the term reflected only differences in languages and customs.
In cross-sectional (e.g. diagnostic) studies, minor underestimation is unimportant, as the difference in specific binding between target (e.g. cortical) and reference regions would be high.
In principle, the system in question must finally reach the thermodynamically stable equilibrium state, in which there are no fluxes and the differences in diffusivities are unimportant.
Lehmann et al. do not clearly delineate how their models differ from ours, and in some places, seem to imply that they are structurally similar, or that the differences in assumptions are unimportant.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com