Critically, Horenstein et al. (2009) showed that bilateral activation was not necessarily the consequence of mirroring (i.e. movement of both hands during the unilateral task) by measuring movements of both hands using fiber-optic gloves.
Dettmers and colleagues interpreted the negative response at the lower force level as transcallosal inhibition, which is essential for the execution of a unilateral task.
115 116 The motion tracking data will also be used to determine the time from presentation to first contact, time from first contact to grasp and approach velocity on the unilateral task.
In future research registration of the time to failure would improve the data from unilateral balance tasks and a test of correlations with age and intensity, duration or site of pain could be interesting.
During a unilateral motor task, IHI suppresses undesired activity in the 'inactive' hemisphere and in a bimanual task.
The five mice achieved the criterion by 21 days for the unilateral stimulation task (broken line in Fig. 1C) and by 46 days for the bilateral stimulation task (solid line in Fig. 1C).
As a preliminary to studying pathological control of gait timing, we designed an experiment with four synchronisation tasks, unilateral heel tapping in sitting, bilateral heel tapping in sitting, bilateral heel tapping in standing, and stepping on the spot, in order to examine the influence of biomechanical constraints on metronome timing.
This transcallosal inhibition seems to play a crucial role in suppressing mirror activation of the ipsilateral motor cortex during unilateral hand motor tasks (Nass 1985).
The present results are in line with several previous findings involving other unilateral lower limb tasks such as static balance control (Hoffman et al. 1998; Lin et al. 2009) and unilateral squatting exercise (McCurdy and Langford 2005).
