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Unilateral expression of TDP-43WT in postmitotic motor neurons for 6 days triggered loss of roughly 30% Isl1/2+ spinal motor neurons relative to the untransfected control hemicord (Fig. 5B).
These elements might explain the age of onset and unilateral expression of the disease.
One of the molecular markers that allows one to detect left-right asymmetry in early embryos before any distinct morphological sign of left-right asymmetry shows up is unilateral expression of Nodal in the left lateral plate mesoderm of the early E8.5 mouse embryo [ 58, 59].
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Yes, in part such engagements may constrain unilateral expressions of sovereignty, but then can the U.S. expect others to act responsibly?
This case represents the unusual unilateral manifestation of the syndrome.
However, the moderate expression of unilateral tumors is preserved as well as the bias of affected males.
We found that a unilateral 6-hydroxydopamine lesion reduced expression of G protein-coupled receptor kinase 6 and â-arrestin-1 protein in the lesioned striatum.
In Vorderwald × Montbéliarde cattle phenotypic expression of CLJ includes unilateral (right- or left-sided) and bilateral cases.
With the exception of the unilateral trait expression in the CC sample, similar general patterns of degeneration were found in all four study samples (i.e., bilateral trait expression, suggested need for sexually dimorphic criteria, and statistically significant correlation between surface feature and age-at-death).
DOI: http://dx.doi.org/10.7554/eLife.11190.010 Unilateral vHP ghrelin (300 pmol) administration robustly increased expression of the neural activation marker Fos in the ipsilateral LHA compared to vehicle treatment (p<0.01 vs. vehicle and vs. contralateral LHA).
In all animals tested, a single, unilateral injection of the viral particles resulted in the expression of the Ndi1 protein in the entire SN spanning 1.8 mm sagittally.
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