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Although parasite prevalence and genetic diversity generally conformed to expectations for an island system, we did not find evidence for a pattern of uniformly altered immune responses in island taxa, even amongst endemic taxa with the longest residence times.
Detailed inspection of expression map and evaluation of individual gene expression profiles showed, that although defined as significant, majority of the identified genes was not uniformly altered across all the patient samples.
Given this difference in repeat location and considering the involvement of epigenetic changes, the transcription level of each variant may not be uniformly altered by methylation, thereby resulting in different disease courses and/or biological outcomes.
We are beginning to explore, amongst the various genes whose expression in prostate cancer cells is uniformly altered by forced expression of C/EBPα, those genes that may contribute to the loss of AR expression and which may provide therapeutic targets for the difficult clinical problem of hormonal independence.
The uniformly altered proprotein convertase profile in liver metastases is observed only in a fraction of primary colon cancers, suggesting possible selection processes involving PCs during metastasis as well as an active role of PCs in liver metastasis.
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regulates the gene expression level, and its abrogation will uniformly alter the gene expression in the affected cells.
The major finding from this study is that the seemingly benign changes resulting from a short period of controlled overeating were all appropriately, uniformly and significantly altered as hypothesized, equivocally elevating cardiovascular risk of the participants.
Most modern carbonate platforms lack allogenic catchments, allowing rainfall to recharge the aquifer uniformly without sufficiently altering head gradients to drive exchange between conduits and aquifers.
However, the mechanical behavior changed when the shear loading condition was altered to distribute the load more uniformly between all truss members and the measured shear modulus was aligned with predicted values.
The missense mutation altered an amino acid residue that is uniformly conserved from Escherichia coli to Homo sapiens (humans).
The CCSphase scores were not uniformly changed in some patients, suggesting that cell cycle phase distributions were also altered.
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CEO of Professional Science Editing for Scientists @ prosciediting.com