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It must be kept in mind that polymorphisms may only be the reflect of unidentified variations, occurring at a distance from the SNP studied, and playing the actual mechanistic effect on the cellular properties observed.
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First, we can not completely exclude the possibility that unidentified variation in patient characteristics between sites may have led to residual confounding of the observed differences in participation rates.
Two ALL patients showing side-effects were wild-type, indicating presence of unidentified rare variations.
The somewhat lower re-gained detectability of pBV43-D-R170K and pBV60-D-R170K and the only two-fold (rather than complete) loss off pBV38-D-K170R signal suggest that additional, unidentified epitope variations in these VLPs also play a role in detection by this test.
This variation may represent true variation of structurally stable constructs, or there may be unidentified structural variation due to response shifts from changing values or beliefs of respondents [ 33], possibly mediated by alterations in cognitive processing after heart surgery.
They estimated that as yet unidentified common variation (with similar effect sizes to those already found) will eventually account for ~20% of the heritable variation, but detecting these would require a sample size of 500,000 individuals.
We hypothesize that these genetic variants, all of them being silent mutations, are in linkage disequilibrium with another yet unidentified functional variation in the AdipoR2 gene.
We cannot say with confidence whether these haplotypes represent DNA damage, error in the PCR reaction, or real but unidentified polymorphic variation in plants.
The nature of the putative regulators of these coexpressions remains elusive, but it seems plausible that the regulation of the system as a whole, and not just the constitutive and differential expression levels of isolated genes, is the one affected by unidentified genetic variation.
We detected 7 previously unidentified non-synonymous variations of SEZ6L2 in ASD patients.
During thalassemia screening, a previously unidentified α2 gene variation in α-globin gene cluster was isolated.
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