Unfortunately, patients chronically treated with topical glucocorticoids develop side effects, including cutaneous atrophy which affects all skin compartments and compromises the barrier function of the skin.
Unfortunately, as many patients treated with anti-angiogenic agents/VEGF inhibitors eventually relapse, the benefit from VEGF targeted therapy can be relatively short.
Unfortunately, most patients are treated with a "one size fits all" approach.
Unfortunately some foals were treated with antibiotics during a severe period of illness which may have an impact on the subsequent microbial profile in faeces.
Unfortunately, most PCa patients treated with ADT eventually acquire castration-resistant phenotype, a form, which is highly aggressive and unresponsive to other therapies (Joly and Tannock, 2004; Sridhar et al, 2013).
Unfortunately, the majority of patients treated with AIs eventually develop resistance.
Unfortunately, the majority of patients treated with AIs eventually develop resistance, inevitably resulting in patient relapse and, ultimately, death.
Unfortunately, the majority of patients treated with endocrine therapy eventually develop resistance, leading to disease progression and death.
Unfortunately, one third of women treated with any of these treatments will relapse (Musgrove and Sutherland 2009).
Unfortunately, the girl was not treated with antimicrobial drugs between these episodes because the samples arrived together at the laboratory for molecular diagnosis.
