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"unfortunate side effects" is a correct and usable part of a sentence in written English.
You can use it when referring to the negative outcomes or consequences that result from something. For example: "The drug was initially seen as a medical breakthrough, but it soon became clear that it had some unfortunate side effects."
Exact(26)
"However, there were unfortunate side effects.
Its unfortunate side effects are legion.
There are going to be unfortunate side effects".
One unfortunate side effects of this project, which was assigned over the years, was that several students could not eat chicken again -- many to this day.
Out-of-wedlock children, in this worldview, become unfortunate side effects of the sexual license designed to protect the marital children.
Sex-attractant pheromones can sometimes have unfortunate side effects for the insect producing them, because they can be used by other organisms to locate the insects.
Similar(32)
That is an unfortunate side effect of the change.
Meanwhile, the 2008 law is having an unfortunate side effect.
This may constitute just deserts, but it has the unfortunate side effect of punishing the reader.
The transformation is an unfortunate side effect of the latest party drug.
"Shutting down the site will be an unfortunate side effect for them".
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com