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The reasons for this are unclear; as lignin content is under both environmental and developmental control it may be that unforeseen variation in growth conditions or sampling effects influenced the results.
From a practical perspective, differences in GTM profiles and metabolism within putatively isogenic mice could result in significant unforeseen variation in the effects of drug treatment in experimental animals and ultimately in humans.
Together, these two discoveries suggest that unforeseen variation in isoprenoid metabolism may be widespread in nature.
There is also an "unforeseen" variation approach for those variations that are not listed in either the guideline or the regulation and for which the type IB by default is uncertain or controversial and believed to be a lower category than a type II variation.
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Flexibility can be understood as the ability of a power system to "respond rapidly to large fluctuations in demand and supply, both scheduled and unforeseen variations and events" ([3] p. 13).
These structural variations reveal an unforeseen pharmacophore profile for the chemical antagonism of WDR5.
Further, the ready availability of dense single nucleotide polymorphism arrays (i.e. SNP chips) has given rise to hitherto unforeseen opportunities to dissect this between-host variation and identify possible genes contributing to this variation using genome wide association studies [4].
Floating dry docks have the initial advantage that they can be built and fully equipped in shipyard and factory conditions, in which their construction is not subject to unforeseen hazards arising from weather and variations in the ground conditions from those anticipated during design.
Conversely, consistent and evolutionarily widespread lack of trait variation in some directions may reveal unforeseen and unavoidable constraints.
This variation in detection rates could have been due to the unforeseen nonspecificity of the real-time PCR, or to the inherent lower sensitivity of conventional PCRs, because most real-time PCR positive samples produced late signals at cycle threshold values ≈40.
Despite the regularity patterns observed in human mobility, variations over time will exist due to social events or unforeseen circumstances such as travel disruptions.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com