Russia today has a glass-like quality to it: rigid and fragile at the same time, and liable to develop cracks in unforeseen places.
Neither the network nor LivePlanet had much time to develop the idea, and there were unforeseen snags.
Therefore, it is prudent to think beyond plasma leak as the main pathology of dengue infection and attempts should be made to develop other treatment modalities to prevent and manage unforeseen fatal complications of dengue infection.
Even though, fluid management is the mainstay of treatment in dengue infection, attempts should be made to develop other treatment modalities to prevent and manage unforeseen fatal complications of dengue infection.
Are the Japanese, the first to develop and broadly practice time-based competition, now stumbling into an unforeseen dark side?
This demonstrates that, whilst it is important to develop plans for the assessment of fidelity to treatment delivery at the study design stage, it is necessary to remain flexible and adapt the planned method in light of unforeseen issues.
Among the CENTRAL trials, I found no reports of adverse treatment outcomes from acupuncture in Japan or the U.S., whereas there were several trials of herbal medicine in the U.S. where unforeseen difficulties developed.
But that's not to say it's going to pass everywhere it gets onto the ballot, or that unforeseen problems may indeed develop which perhaps might require different rules or regulations.
Monitoring clinical trials is a dynamic process which requires flexibility to respond to unforeseen developments.
"We remain to be convinced the Army 2020 plan represents a fully thought-through and tested concept which will allow the Army to counter emerging and uncertain threats and develop capability to deal with unforeseen circumstances".
The challenging mission to demolish the satellite on the fringes of space will rely on an unforeseen use of ship-based weapons developed to defend against ballistic missile attacks.
