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But trading in the pristine weather of L.A. for the unpredictability of New York City, along with the logistics, made the week of party-hopping an often chilly experience as events unfolded across busy Manhattan.
The Myall Creek Massacre, as it came to be known, was not the first of the hundreds, perhaps thousands, of such crimes that unfolded across the colonial frontier between the first inhabitants, soldiers, settlers, vigilante groups and Indigenous "black police".
At Le Bistrot d'en Face, with club music playing low, dozens of conversations almost exclusively in French unfolded across the crowd, as waiters sprinted around with dishes like calamari and moules gratinee.
The original trilogy (and even the much-maligned prequel trilogy), had a wonderfully structured story arc that perfectly unfolded across their three films.
It was a miracle the Paris conference even took place, given the terror that unfolded across the city just weeks before.
This chaotic interaction, at once surreal and uplifting, was emblematic of the three days that unfolded across Afghanistan recently, when the 17-year war that has relentlessly ravaged this country was temporarily put on hold.
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As the story has unfolded, people across the globe, more importantly, Americans across the country, have come to the realization that the course of human life, more importantly, American life has fundamentally changed.
The Sec protein translocation system is responsible for the translocation of unfolded protein across the cell membrane into the periplasmic space.
The major difference between these two export systems is that the Sec apparatus translocates unfolded polypeptides across the membrane, whereas the Tat complex transports already folded proteins.
These proteins assist with the folding of nascent peptides and the de-novo folding of denatured proteins, the transport of unfolded proteins across membranes, quality control and conformational changes that affect function [ 36].
The biogenesis of an outer membrane β-barrel protein (OMP) begins with the translocation of the newly synthesized, unfolded protein across the IM into the periplasm via the Sec translocation machinery, which requires a cleavable general SP. Once the unfolded OMP reaches the periplasm, it uses the SurA or Skp-DegP pathway to reach the OM.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com