The "natural" prognosis often being unfavourable, with conventional therapeutic methods having relatively limited effects, has encouraged researchers to work on new alternatives.
At the same time the aortic valve replacement (SAVR) was not indicated in about 1/3 of the patients, though the prognosis of conservatively treated patients is very unfavourable with one-year mortality rate of 50%.
Critical response of the era was generally unfavourable, with Lester Bangs delivering an ambivalent review of Master of Reality in Rolling Stone, describing the closing song "Children of the Grave" as "naïve, simplistic, repetitive, absolute doggerel – but in the tradition [of rock'n'roll] .
Diarrhoea was the only QoL item that was unfavourable with the weekly treatment.
Nevertheless, the prognosis is unfavourable with or without treatment (survival rate from 6 to 16 months).
However, the risk benefit ratio of BCG vaccination becomes increasingly unfavourable with decreasing TB transmission rate [ 83– 83].
The prognosis for patients with metastatic disease is unfavourable with a 3-year disease-free survival of less than 5%.
In the unit, his evolution was rapidly unfavourable with the occurrence of multiple and repeated episodes of ventricular fibrillation.
The number of '+'s or '-'s indicates the degree to which the drug is favourable or unfavourable with respect to the parameter under question.
This reduction is highly challenging and thermodynamically unfavourable, with a midpoint reduction potential of −450 mV for the Co2+/1+ coupled reaction [ 4, 5].
However, in primary refractory or relapsed AML, the prognosis is generally unfavourable, with salvage chemotherapy giving a remission rate of merely 10 40%.
