Sentence examples for unfavourable secondary from inspiring English sources

These sequence optimisations reduce unfavourable secondary structures in mRNA and thus improve the success rate of translation and protein expression.

To solve this problem, we made use of the ProteoExpert software, which predicts possible sequence-related problems and proposes optimised sequences with potentially reduced unfavourable secondary structures [ 18, 20].

This secondary bending phenomenon is unfavourable for the fatigue properties of a structure.

The purpose of this study was to explore the association of genetic polymorphisms of LEP or LEPR with an unfavourable outcome (death) in patients with non-appendicular secondary peritonitis.

This was found again when analysed only with tumour border configuration, suggesting that the prognostic effect of loss of membranous CD166 in the tumour centre may be secondary to its association with these unfavourable prognostic features, in particular with the infiltrating tumour growth pattern.

On study completion, all schools allocated to the control group will be directed to the e-Bug website to enable them to download and deliver the chlamydia lesson if they wish providing the findings do not indicate that the lesson has any detrimental effects i.e. unfavourable changes in any of the primary or secondary outcome measures.

The secondary selection criteria included conjunctival melanoma in unfavourable locations (eg, forniceal, caruncular or tarsal conjunctiva) and recurrent conjunctival melanoma associated with the 'florid phase' of PAM.

The SNPs showing a significant risk effect were then incorporated into a secondary analysis for the total number of unfavourable genotype groups carried, adjusting for the same factors listed above.

Studies report unfavourable outcomes in many patients [ 3- 5][ 6], high costs in terms of secondary care and sick leave [ 7] and frequent occurrence in the workplace [ 8].

These results seem to indicate that the unfavourable prognostic impact of loss of membranous CD44s within the main tumour body may be secondary to its association with T classification, lymph node metastasis, the presence of vascular invasion, and the infiltrating growth pattern.

For example, hybridisation efficiency is reduced when probes and their targets form secondary structures, when probes have unresponsive binding affinities, when interactions with fluorescent labels are unfavourable, and when non-specific binding occurs [ 6, 27].