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In 1964, he resigned voluntarily following unfavourable observations made against the Government of Andhra Pradesh by the Supreme Court in the Bus Routes Nationalisation case.
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It produces good results and generalizes well even if the ratio between the number of variables and the number of observations becomes very unfavourable or in the presence of highly correlated predictors.
Any abnormal health observation that was unfavourable, unintended and occurred after enrolment, regardless of whether it was considered as an MCTD- or a placebo diet-related event, was reported to the investigator and documented (online Supplementary Table S1).
These observations have been ascribed partly to unfavourable environmental conditions (gas super-saturation) and the problem has to a large extent been solved.
Clinical observations suggested that low albumin might indicate an unfavourable prognosis, especially in the near future (Nixon et al, 1980; Hill, 1987; Heys et al, 1992).
In fact, unfavourable alterations in filtering bleb morphology following phacoemulsification, consistent with our observations, were already reported.
However, unfavourable background accumulation and high hepatobiliary excretion were observed.
The success of the voyage depended on the pin-point accuracy of Worsley's navigation, using observations that would have to be made in the most unfavourable of conditions.
This corresponds to the observation that larger offspring are produced in response to unfavourable environmental conditions in Daphnia [e.g. [ 45, 46]], as well as in other organisms [e.g. [ 47- 49]].
These and other observations have spawned the 'RBC storage lesion' hypothesis, which proposes that unfavourable cellular changes occur during the storage of RBCs [ 11].
This observation supports the hypothesis that iron deficiency may provide an unfavourable environment for bacterial growth [23].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com