Sentence examples for unfavourable features from inspiring English sources

BRCA1-associated breast tumours frequently show unfavourable features, ie poor differentiation, high proliferation indices, aneuploidy, ER- and PgR negativity, and TP53 positivity.

In the present study of thick cutaneous melanomas, increased mitotic count and Ki-67 expression were both associated with known unfavourable features, such as increased tumor thickness, Clark's levels of invasion, presence of tumor ulceration, tumor necrosis and vascular invasion.

The NCCN Practice Guidelines 2007 http://www.nccn.org recommended adjuvant chemotherapy only in tumours between 6 mm and 10 mm without metastases in lymph nodes (pT1b pN0): in ER-negative pT1b pN0 (both HER2-negative and HER2-positive) and, in addition to hormonal therapy, in ER positive pT1b pN0 moderate/poorly differentiated or with unfavourable features (both HER2-negative and HER2-positive).

Patients with unfavourable histopathologic features had significantly worse OS and RFS than those with favourable features (96.4 vs 75.9%, P<0.0004; and 85.5 vs 61.2%, P<0.0035, respectively) (Table 5).

Patients with CHF were divided into 4 subgroups according to ascending quartiles of plasma CT-proET-1, and clinical characteristics of these subgroups are presented in Table 2. Patients with CHF with the highest plasma CT-proET-1 (>upper quartile) had particularly high plasma NT-proBNP as compared to the 3 other subgroups and were characterised by unfavourable clinical features.

A considerable number presented with unfavourable prognostic features.

In breast cancer survivin and NAIP overexpression has been associated in unfavourable clinical features [ 17].

Limited oral cancer in general is treated surgically, using postoperative radiotherapy or chemoradiation in the case of unfavourable histopathological features.

Unfavourable environmental features might limit the daily activities of older people increasing the risk of cognitive decline.

We hypothesise that unfavourable municipal features (eg, fewer GPs or fewer available places for rehabilitation) are associated with higher risk of mortality after accounting for patients' characteristics.

Choie et al. [ 17] described overexpression of NAIP in breast cancer patients with unfavourable clinical features, suggesting that NAIP would play a role in the disease manifestation.