Sentence examples for unexplored target from inspiring English sources

As such, this may after circulation represent a novel and unexplored target for prevention and treatment of neurodegenerative diseases.

A validated but as yet unexplored target for new antibiotics is dihydrodipicolinate reductase (DHDPR), an enzyme that catalyzes the second step of the lysine biosynthesis pathway in bacteria.

Monocyte heterogeneity may represent an as yet unexplored target for imaging and treatment [8], [14], but currently no clinical assays can simultaneously discriminate between monocyte subsets.

However, NS2 protease activity remains an unexplored target.

By comparing the obtained disruption targets with lists of drug molecules we find that many of these targets can be acted upon by existing drug compounds, whereas the remaining ones point at so-far unexplored targets.

Other less annotated genes represent new, still unexplored targets for intervention at the early stages of inhalational anthrax.

Small non-coding miRNAs have rapidly emerged as an important feature of gene regulatory cascades in different tissues, including the brain [ 8], and thus seemed obvious, if unexplored, targets for investigation in songbirds.

Although the physiological impact of calcium, copper, and amino acid availability on cell wall structure has been previously described, the genes involved in transportation (and thus the putative availability of these metal ions and lignin precursors to developing cell walls) provide hitherto unexplored targets for modulating cell wall biosynthesis.

With the increasing emergence of multidrug-resistant bacterial infections in the past several decades, there has been a critical need for the identification of novel antibiotics directed towards previously unexplored targets, such as those other than cell wall, nucleic acid, or protein biosynthesis.

Unexplored issues (target CO2 purity, cost curves, hybrid processes, role of water, minor components) are finally exposed as major research targets.

The detailed features of these networks and how they are impaired by oncogenic mutations can provide important clues for unexplored drug target sites on Ras [ 2].