We cannot exclude that differences in time-course response of individual Smads to HBR may reflect inherent changes in these still largely unexplored patterning of post-transcriptional modifications.
These largely-unexplored patterns of transcription are typically explained either by the existence of regulatory elements internal to the TE (internal enhancer model) or by the co-option of external cellular regulatory elements in the vicinity of a TE insertion (enhancer trap model) [ 39, 41].
These findings identify hitherto unexplored transcriptional patterns and undocumented transcripts in genetically diverse mice.
Finally, the abundant prophage sequences present in the P. fluorescens genome (Loper et al. 2012) provide an opportunity to study the unexplored mutation patterns of prophages.
"We have to produce people who can look at chaos with the intellectual confidence it takes to explore it from unexplored angles and discover patterns," says Burridge.
The design of gridshells is subject to strong mechanical and fabrication constraints, which remain largely unexplored for non-regular patterns.
A growing body of research has documented the local impact of employee non-compete agreements, but their effect on interstate migration patterns remains unexplored.
It has also shown that most of the existing literature on this matter is based on surveys or observations of reduced samples of individuals, while large scale studies on social network sites data still leave many relevant aspects, such as age patterns, mostly unexplored.
Such patterns remain unexplored for P. downsi.
As pinpointed by Allen et al. [ 15], such patterns are almost unexplored in mycorrhizal fungi (but see [ 16]).
In particular, the results shown in this paper (e.g., Figs. 2 3 5) reveal a wide range of design tunability of the graphene snap-through instability on substrates through substrate surface patterning and interfacial adhesion tailoring, which offers abundant unexplored potential toward the design of functional graphene device components (e.g., nano-switches, nano-resonators).
