Wild primate populations, an unexplored source of information regarding emerging infectious disease, may hold valuable clues to the origins and evolution of some important pathogens.
The nitrilases from the bacterial origin have been unexplored for hydrolysing 4-CP to INA, whereas its isomer 3-CP has been used as substrate for the synthesis of nicotinic acid ([Mathew et al. 1988, Vaughan et al. 1989, Almatawah and Cowan, 1999, Prasad et al. 2007, Sharma et al. 2006, 2011]).
Although unexplored, proximity of country of origin to country of delivery may be a factor influencing selective migration patterns.
Further, the distortion of SF frequencies in regions populated with individuals with different specific continental origins is largely unexplored.
Previously, we showed that plethodontid salamander genomes accumulate higher levels of long terminal repeat (LTR) retrotransposons than do other vertebrates, although the evolutionary origins of such sequences remained unexplored.
The timing and the geography of the origin of the European populations remain unexplored in phylogeographic terms, whereas allozyme and initial mitochondrial data have confirmed their Pacific species identity [ 8, 12, 13].
Explanations for this unidentified genetic 'dark matter' of cancer include phenotype ascertainment issues, limited power, gene gene and gene environment interactions, population heterogeneity, parent-of-origin-specific effects, and rare and unexplored variants.
While the native species that inhabit urban environments have received some attention in the pest control literature [23], [24], their origins and basic biology remain essentially unexplored.
However, the evolutionary origins of such abundant TEs remained unexplored.
The origins of different metabolic pathways in the eukaryotes are relatively unexplored areas, in particular in fungi that represent the closest lineage to animals [15].
