However, looking at the effect-sizes, unexpectedly, negative effect sizes resulted.
Histone modifications, the H3K27M cancer mutation, and inclusion of JARID2 or EZH1 in the PRC2 complex have unexpectedly minor effects on PRC2-nucleosome binding.
The variation in the mass transport limited steady state current (measured at the collector electrode) with addition/removal of supporting electrolyte remains low (compared to unexpectedly stronger effects caused by the switch between reduction and oxidation conditions at the collector electrode).
Unexpectedly, Hsp90 effects were remarkably specific to the most invariant quantitative traits showing that whether Hsp90-buffered traits are quantitative or qualitative, they are threshold traits with a continuous underlying distribution of genetic and environmental effects (liability) determining the probability that they would be variably expressed.
Unexpectedly, the effects of isometric contractions were also independent of eIF4F complex formation.
Unexpectedly, the effects of PCB exposure appeared to be attenuated by coexposure to MeHg.
Unexpectedly, the effects of TFEB were almost abolished when autophagy was genetically suppressed.
Nevertheless, unexpectedly, the effects of miR-221 and miR-222 introduction in other five cancer cell lines significantly differed between cell lines.
In the present study, we have identified unexpectedly potent effects of a ubiquitously used chemical, BADGE, on adipogenesis in MSCs at nanomolar levels.
Not unexpectedly, the effects propagated through gap junctions superseded those that are disseminated through extracellular secretion, as this type of communication surmounts the barrier presented by the intervening plasma membrane.
