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An entire career can be lost in a single gaffe or an unexpected shift in the national mood.
This modest chemical change results in a very significant and unexpected shift in the selectivity of COX inhibition, creating a molecule that is a highly potent, slow, tight-binding inhibitor of COX-2 lacking significant COX-1 inhibitory activity.
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When in March the bureau began releasing data from the 2000 census, planners started noticing unexpected shifts in the population counts in a number of places.
Unexpected shifts in the numbers and abilities of candidates caused a dip in results for several major subjects including English and sciences.
The film and its conceptual nature, much like Bismuth's visual art, reflects his desire to better understand the world by creating unexpected shifts in the everyday meaning of things, in order to question how we perceive.
Click here to watch Haim's Forever What we said: "Their method varies song by song: in I Should Live in Salt, it's with an undertow of intricate details, stuttering rhythms and winding woodwind; in Fireproof, it's with melodies and percussion that refuse to align; in Don't Swallow the Cup, it's with unexpected shifts in the song's structure.
The personnel consequences of the Treasury's unexpected shift in strategy in the rescue plan — from the purchase of so-called troubled assets on financial balance sheets to the injection of capital directly into financial institutions — also drew attention from the auditors, those briefed on the study said.
The Iranian reaction to the letter provides critical insight into a decisive and unexpected shift in strategy by the moderate new president as Iran struggles to restore vitality to its economy and undo years of hostile relations with most of the world under the former president, Mahmoud Ahmadinejad.
His signature move is to find himself propelled, by a song's unexpected shift in tone, by the delivery of a line or maybe even just a word, or by some unexpected cultural resonance to a famous or obscure historical event, into a newly charged landscape where everything is at stake.
Someone who used their currency to buy a claim on dollars five years ago may be able to buy the same bundle of American goods as ever, but the unexpected shift in America's exchange rates means that the dollars on which they have a claim will buy fewer goods in their home country than they'd originally believed would be the case.
The massive and unexpected shift in refugees' location has disrupted the relief effort.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com