Sentence examples for unexpected mutations from inspiring English sources

They could look at all of Mr. Lanza's genes, searching for something unusual like gene duplications or deletions or unexpected mutations, or they might determine the sequence of his entire genome, the genes and the vast regions of DNA that are not genes, in an extended search for aberrations that could determine which genes are active and how active they are.

He successfully corrected the gene responsible for the blood disorder β-thalassaemia (a potentially fatal blood disorder), though some unexpected mutations were generated.

Additionally, recombination may occur with similar but not identical endogenous sequences, leading to unexpected mutations, as we found in human tripronuclear zygotes in which HBB recombined with HBD (Liang et al., 2015).

In contrast, the reported homoplasmic variation does not exhibit any excess or unexpected mutations: by and large, it matches the natural variation in the general population.

Introduced mutations were considered to be detectable if their z-score was higher than all of the significance scores for unexpected mutations (false positives) on the control samples.

Second, in the capillary verification experiments, about 20 kb was sequenced from both chromosomes, and no unexpected mutations were discovered.

Hence, the potential risk of heritable disease should be considered, especially in the HRPT2 mutated case for which unexpected mutation carriers are known to occur.

After decades of a Conservative leaning press, ended by the unexpected mutation of the Murdoch Sun into a Labour supporter in 1997, the endorsement in 2001 of New Labour, in circulation terms, by over 91% of the national daily press went almost without comment.

Finally, a D516Y substitution was detected in association with an unexpected mutation, G523W, not tiled on the DNA probe array, but which could be detected by analysing the hybridisation pattern obtained with the wild-type probes covering codon 523.

When the introduced mutations were mixed at 1%, five of the six had z-scores greater than any unexpected mutation.

C70V was an unexpected mutation that resulted from a PCR error but turned out to be crucial for the Q69M effect on Sapphire as without it SapphireQ69M remained non-fluorescent.