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H' is maximized when all genotypes are at equal frequency and decreases with decreasing number of genotypes or uneven frequencies.
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Here the input was repetitive, and therefore with less sampling of natural statistics, contained certain patterns with uneven frequency spectra.
Each prototype word is assigned a prior likelihood to be observed thus capturing the uneven frequency of occurrence of different words in natural speech.
During one such genomic study, we observed a very uneven frequency profile of individual HNF4α binding sequences [ 42].
Thirdly, lateral gene transfer, commoner in bacteria than eukaryotes, but of uneven frequency, also places occasional branches incorrectly on single-gene trees [ 11, 12].
The difference between the average number of observed alleles and effective number of alleles was due to the uneven frequency of each allele [ 50].
In spite of the high number of patients and because of the uneven frequency of early RA and UA data, we used nonparametric tests for statistical analysis of continuous variables.
In theory, each of the estimates can be recorded at different (or uneven) sampling frequencies.
Biases may result from phenomena such as pattern heterogeneity and uneven base frequencies, and their exploration will help us to understand cases of incongruent relationships.
Unless averaging is performed, the analyses will be affected by noise from individual fixed markers that do not necessarily indicate a selective sweep but rather could be attributable to, for example, uneven allele frequencies across haplotypes in the founding population leading to early fixation for alternative alleles in the selected lines by drift.
The SNP in exon 7 was excluded from further analyses, because of the uneven allele frequency distribution with a minor allele frequency of 0.0013.
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