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The second problem is caused by uneven case distribution, such that similar problems may have dissimilar solutions.
Another point of view, an uneven case distribution was named as potential obstacle.
This procedure may be affected by a lack of accurate diagnosis, imprecise symptoms, uneven case detection efforts, and reporting bias; therefore a spatially smoothed approach was used for reducing spurious outliers.
This geographical pattern of uneven case load was already noted in a previous study reporting AEP data from 2007 2009 [ 4], and remained in this study with all known cases of AEP from 1995 to 2012 included.
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Although legal precedent (like our shockingly and necessarily clear laws against willing property to pets) weighed against Tommy in America, beyond our shores there have been several prominent, if very uneven, cases setting international precedents for ape rights.
We divided the cats into uneven in case they might refuse to eat the experimental diet.
Differential intentions towards children of different sexes, ages, degree of relatedness and parentage may become important when resources are strained, leading to uneven reallocations (Case, Paxson, & Ableidinger, 2004).
Note that if the weight of the surface building is uneven like the case shown in Fig. 4, the differential settlement can be observed in case of the foundation bearing layer being liquefied during earthquakes.
Logistic regression analysis of case-control status on batch and GC50PCT indicated a strong batch effect (p<10e−7), largely driven by an uneven allocation of cases and controls in batch four and a batch-GC50PCT interaction (p = 0.02).
The protective haplotype had an uneven distribution between cases and controls and only three (10%) of the controls were homozygous.
‡Tertiles are computed relative to a larger reference population, which accounts for the uneven distribution of cases.
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