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Linkage studies have unequivocally pointed out the region harbouring the mutation responsible for the phenotype.
Surprisingly, evidence from both gain- and loss-of-function experiments unequivocally pointed to Cx26 as the sole connexin gene responsible for the observed effects on LR asymmetry.
However, those first studies did not document a physical interaction between PARs 1 and 4, although the data unequivocally pointed to such interactions.
At this stage, Lyon had multiple layers of data, including a functional assay in yeast, which unequivocally pointed to the causative gene and showed that the expectant mother is a carrier.
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Today, the Daily Mirror reported Wickramasinghe as saying, "Data from the comet seems to unequivocally point to micro-organisms being involved".
Since the amino acid measurements were performed in the same samples, these data unequivocally point to different release mechanisms or different cellular sources.
It is apparent that the collective findings in this area do not unequivocally point to one pathway or exclude another.
As a matter of fact, the available literature on the association with human traits does not unequivocally point to adiponectin as a metabolic and vascular protecting hormone.
The organismal developmental stage and the tissue-specific expression observed in some satDNAs unequivocally point to a regulatory role for these transcripts (Vourc'h and Biamonti 2011).
The outcome of these studies unequivocally points to FGF23 as a robust marker of disease surrogate markers as well as hard clinical end points including mortality and cardiovascular events.
When the findings of the glucose-induced, short-lived increase in CT release and of the abilities of both metyrapone and RU486 to abolish the preischemic hyperglycemia-aggravated postischemic damage are taken together, they unequivocally point at CT as the culprit behind the glucose paradox of cerebral ischemia.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com