Conclusions: As a consequence, in these patients DNA sequencing or RFLP analysis is necessary to unequivocally assign the correct HFE genotype.
However, further investigation with tools that enable the drawing of reaction schemes would be necessary to unequivocally determine whether their presence would change the response to the cues and No Template condition.
Further analyses will be necessary to unequivocally associate CaMNUC32 with PCD.
223b Despite some evidence that histone proteins can be ADP-ribosylated on arginine residues, further studies are necessary to unequivocally prove the presence of ADP-ribosylated histones and to identify the underlying transferase enzyme(s).
Furthermore, large numbers of genetic loci are necessary to unequivocally assign parentage, which may be very useful for establishing genetically diverse populations of endangered species through the augmentation of existing genetically depauperate populations or the creation of new populations.
Although coexpression with RAMP-1 is necessary to unequivocally demonstrate the presence of functional CGRP receptors, our demonstration of RAMP-1 mRNA expression in L3 L4 DRGs partially addresses this issue.
A direct head-to-head trial will be necessary to unequivocally conclude that a variable dosing regimen using OCT is noninferior to a fixed monthly dosing regimen (Fung et al. 2007b).
Finally, the use of more than two preference categories is a necessary precondition to unequivocally determining any modulatory influence of brand preference on neural activity patterns.
Second, because quasispecies effects are second-order, it may be difficult to detect them experimentally, and experiments more sensitive than the ones carried out to date may be necessary to demonstrate their presence unequivocally.
