Sentence examples for unequivocally difficult from inspiring English sources

Sites like Giant, or Faro Mine in the Yukon, or Colomac Mine in the Northwest Territories are unequivocally difficult to remediate and will require decades of pricey palliative care.

Now it would be easy to imagine a scenario though difficult to unequivocally prove where much more efficient genomic colonists started to use larger "resource" vesicles as replication factories that would eventually gain greater autonomy.

Nevertheless, it is difficult to unequivocally attribute extinctions to a species invasion, and the few scientific studies that have done so have been with animal taxa.

Therefore it is difficult to unequivocally determine whether this increase in conservation is a true feature of motif-binding residues.

For these reasons, it is difficult to unequivocally determine accumulated ironoxide nanoparticles in tissues, which appear dark on MR images or in neighborhood of other signal distorting structures.

Therefore, even though it is difficult to unequivocally decide whether bulky mutant residues cause loss of function because they change a critical residue or because they partial unfold the protein, our results suggests that this region is indeed a very critical one for proper 2-HBP-mediated activation of HbpR and that its most essential residues are Thr52, Ile180, Glu184 and Cys187.

Drug trials against chronic stage infections are particularly challenging because it is difficult to unequivocally demonstrate sterile cure.

However, it is difficult to unequivocally validate this possibility without specific technology that can efficiently separate different alleles in cells.

It is difficult to unequivocally interpret levels of tissue-specific specific transcript between wild type embryos and embryos with severe developmental defects.

Without a quantitative knowledge of the gases produced and their sources and sinks, it is difficult to unequivocally estimate gas fluxes through modeling approaches.

However, it is difficult to unequivocally establish the process of genome rearrangement in the C. japonica cp genome based solely on the positional information of these repetitive sequences.