Therefore, even though it is difficult to unequivocally decide whether bulky mutant residues cause loss of function because they change a critical residue or because they partial unfold the protein, our results suggests that this region is indeed a very critical one for proper 2-HBP-mediated activation of HbpR and that its most essential residues are Thr52, Ile180, Glu184 and Cys187.
Given, in addition, the above stated differences in the applied methodology, it is not possible to unequivocally decide whether or not these differences indeed reflect natural conditions.
They all share the central idea that a respondent's point of indifference, at which he or she cannot unequivocally decide on a certain judgmental task, enables researchers to measure utility differences via the traded "goods".
It cannot unequivocally be decided whether there are compensatory functional mechanisms when there are sufficiently small morphological defects or whether microperimetry is methodologically limited to detect the earliest functional deficits, or both.
This was a "crucial" experiment, one that decided unequivocally between two competing theories, or classes of theory.
But if you were to ask me which of these two groups -- those single or those married -- seem to have achieved the most success in every area of their lives by the end of their days, I would tell you unequivocally, those who decided their marriage was worth the fight....and fought for it every step of the way.
Much as the International Cricket Council would like us to think that it is important, there are few people who truly believe the one-day international world rankings matter in a form of the game in which there is a championship every four years to decide unequivocally who is best.
We analyzed high spatial density ERP data in order to decide unequivocally whether ERP phenomena can be interpreted in functionally similar terms in these tasks.
A young married couple with local roots, Jenn and Mike Vermeer, said they had decided to support Mr. Santorum only recently after hearing his unequivocally anti-abortion message at an event.
Michele Bachmann decided to simply "step aside," whereas Tim Pawlenty was the only candidate to unequivocally "end" his effort, without even teasing supporters with the semantics of impermanence.
By the 1890s, he decided to build a library on a par with the great European collections, a goal he unequivocally achieved.
