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Therefore, even though it is difficult to unequivocally decide whether bulky mutant residues cause loss of function because they change a critical residue or because they partial unfold the protein, our results suggests that this region is indeed a very critical one for proper 2-HBP-mediated activation of HbpR and that its most essential residues are Thr52, Ile180, Glu184 and Cys187.
Given, in addition, the above stated differences in the applied methodology, it is not possible to unequivocally decide whether or not these differences indeed reflect natural conditions.
They all share the central idea that a respondent's point of indifference, at which he or she cannot unequivocally decide on a certain judgmental task, enables researchers to measure utility differences via the traded "goods".
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It cannot unequivocally be decided whether there are compensatory functional mechanisms when there are sufficiently small morphological defects or whether microperimetry is methodologically limited to detect the earliest functional deficits, or both.
Much as the International Cricket Council would like us to think that it is important, there are few people who truly believe the one-day international world rankings matter in a form of the game in which there is a championship every four years to decide unequivocally who is best.
This was a "crucial" experiment, one that decided unequivocally between two competing theories, or classes of theory.
In 2012, the health secretary Andrew Lansley wrote to all the 211 CCGs pledging unequivocally that they individually would be able to decide, rather than ministers or the NHS regulator, Monitor, when to put contracts out to tender.
If you can't decide between candidates as clearly and unequivocally disparate as Obama and Romney by now, odds are you shouldn't be voting.
The European treaties state unequivocally that euro membership is irreversible unless a country decides to exit not just from the single currency but from the entire EU.
A young married couple with local roots, Jenn and Mike Vermeer, said they had decided to support Mr. Santorum only recently after hearing his unequivocally anti-abortion message at an event.
Michele Bachmann decided to simply "step aside," whereas Tim Pawlenty was the only candidate to unequivocally "end" his effort, without even teasing supporters with the semantics of impermanence.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com