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But oxygen does unequivocally alter the physiological altitude of Everest.
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Altered mRNA levels do not unequivocally indicate altered enzymatic activities, however, nearly all changes showed higher mRNA levels, supporting their proposed function in the sustained surge of free fatty acid metabolism proximal to the site of injury during the hours and days after TBI.
In addition, because we have analyzed bone from end-stage OA, it is difficult to determine unequivocally that the altered gene expression detected in the OA bone is causal or secondary to the disease.
No one from Mr. Buchanan's campaign has said unequivocally that he would not alter the platform or preamble if he was nominated.
The fact that VAChT expression was rescued by the removal of the TK-Neo cassette shows unequivocally that the two loxP sequences that flank the VAChT gene do not alter transcription.
Alter disagrees!
Using this approach, we show unequivocally that AHR and remodeling driven by altered pulmonary gene expression can develop independently of eosinophilia or T-cell recruitment, which is impossible to do in human subjects.
However, because the sex hormones important for controlling the process of spermatogenesis were not altered after BPA treatment, we attempted to unequivocally demonstrate how spermatogenesis is disturbed by BPA exposure.
Analysis of various potential mechanisms, including altered drug transport, detoxification mechanisms and DNA repair [32], did not unequivocally identify the critical cause of the extraordinary sensitivity of TGCT cells.
Although in principle, no obvious candidate genes could be unequivocally related to the exocarp colour break retardation, the 39B3 mutant certainly exhibited altered chlorophyll a and b content.
Thus, the confirmation of altered miRNA expression within individual cells in the native context of a complex tumor lesion is required to unequivocally assign miRNA dysregulation to cancer cells or other cells of the tumor microenvironment.
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