Sentence examples for unequivocal progression from inspiring English sources
An exploratory endpoint also included the evaluation of changes in bone turnover marker levels and the rate of progressive disease in bone, defined as unequivocal progression of a pre-existing bone lesion or the appearance of a new bone lesion [10].
This was due to the appearance of new lesions in 8 patients and due to unequivocal progression of non-target lesions in 2 patients, while all target lesions showed stable disease.
Based on standard Response Evaluation Criteria In Solid Tumors (RECIST) guidelines [50], disease progression was defined as at least 20% increase in the sum of the longest diameters of all target lesions or as the appearance of one or more new lesions and/or unequivocal progression existing non-target lesions.
PD was further divided as to whether lesions were new or demonstrated unequivocal progression.
Progression was defined as development of new lesions or "unequivocal progression" of existing lesions, as defined by the original researchers.
Patients with only non-measurable lesions were considered to have PD when there was unequivocal progression of existing lesions or when new lesions were detected at follow-up.
A positive scan suggested relapsed lymphoma, with true-positive results requiring either biopsy confirmation or unequivocal scan progression.
There is unequivocal evidence that CKD progression can be slowed by optimal management of hypertension and proteinuria [ 21].
The benefits of regular exercise on cardiovascular disease incidence and progression are unequivocal (Warburton et al. 2006).
Progression was defined according to RECIST criteria on tomodensitometry or magnetic resonance imaging (MRI) or on clinical progression when unequivocal (subcutaneous nodules, superficial lymph nodes, spinal cord compression).
Patients randomized to the pazopanib monotherapy arm in Cohort 2 who experienced unequivocal evidence of disease progression were given the option to receive monotherapy lapatinib in an open-label extension phase.
