Unequivocal histological typing and grading of diffuse gliomas is challenging however, especially because the biological diversity of these tumors is difficult to capture in precise microscopic criteria.
Only one study was graded as 5 (unequivocal results).
Sacroiliitis is graded as 0-4 (normal, suspicious changes, minimal abnormality, unequivocal abnormality, total ankylosis).
Low- and high-grade dysplasia (synonym: intraepithelial neoplasia) was defined as unequivocal neoplastic transformation according to previously published criteria (Lewin and Appelman, 1995).
Even if the practical benefit of MRI in pretreatment diagnostics is unequivocal, a diagnostic arthroscopy is of outstanding value when a grading of the cartilage is crucial for a definitive decision regarding therapeutic options in patients with osteoarthritis.
High abundance of HSPB1 was detected in grade IV astrocytoma, particularly in GBM-SS (5 months, Fig. 3d e)) with unequivocal contrast to the weak labeling of a GBM-LS case (27 months, Fig. 3d(f)).
Low- and high-grade dysplasia (synonym: intraepithelial neoplasias; Gabbert et al, 2000) was defined as unequivocal neoplastic transformation according to criteria published previously (Lewin and Appelman, 1995).
The staining was recorded using a semiquantitative and subjective grading, considering both the intensity of staining and the proportion of tumour cells showing unequivocal positive reaction.
The immunohistochemical staining was recorded using a semi-quantitative and subjective grading, considering both the intensity of staining and the proportion of tumor cells showing unequivocal positive reaction.
The nuclear immunohistochemical staining of mitosin was generally fairly strong (Fig. 1), and recorded using a semi-quantitative and subjective grading, considering both the intensity of staining and the proportion of tumor cell nuclei showing unequivocal positive reaction.
