Exact(5)
An unequivocal functional linkage exists between the rate of ribosome biogenesis and the nucleolus ultrastructure.
Although we may lack an unequivocal functional explanation for sleep, the same is not true for the immune system.
An unequivocal functional or molecular association between these two family cases was not found suggesting that the patients probably share another, so far undiagnosed and unknown, predisposing factor.
Additional gene products shown to play a central role in virulence yet are not essential for growth in laboratory conditions or do not have an unequivocal functional annotation represent additional therapeutic targets.
As budding yeast is the only model organism where there is a 1 1 relationship between the cenH3 nucleosome and the microtubule attachment site (Furuyama and Biggins, 2007), any conclusion concerning its composition and structure has an unequivocal functional interpretation.
Similar(55)
Neither of these regions yields unequivocal information for functional classification.
Taken together, these segregation data and, more importantly, the occurrence of the aberrant nodule phenotype in several independent mutation events (especially three, independent point-mutation lines) provides unequivocal evidence that functional SACPD-C is required for normal nodule development in soybean.
To be classified as a case, patients had to exhibit unequivocal macular and functional alterations (i.e. bull's eye maculopathy on funduscopy and/ or optical coherence tomography and/ or fundus autofluorescence imaging, pericentral scotoma in the automated threshold perimetry, pericentrally decreased amplitudes in the multifocal electroretinogram).
The differentiating BMSCs were induced to undergo cardiomyogenic differentiation pathway and were able to express unequivocal electromechanical coupling and functional synchronization with ECMs.
Not only did it indicated that genetic factors contributed to the susceptibility as well as the pathogenesis of KD, but this was the first unequivocal identification of the functional SNP in a new gene (ITPKC).
As a result, this mutation meets all pathogenicity criteria proposed for a homoplasmic mutation: absence from healthy controls, remarkable phylogenetic conservation and unequivocal evidence of a functional defect of the mutant ribosome (9).
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