Every protein signalling network has abundant uncertainty, because every drug can have undiscovered effects, and every time-series experiment can have undiscovered peaks or dips occurring between the observed time points.
Thankfully that title doesn't refer to some undiscovered side effect of vamp-human intimacy, so we begin tonight's episode with a lusty continuation of last week's Sookie-Bill sexy times.
Undiscovered side effects of drugs can have a profound effect on the health of the nation, and electronic health-care databases offer opportunities to speed up the discovery of these side effects.
It is hypothesized that undiscovered core promoter motifs might exist.
If a drug like Prempro, which has been in use for years, still have undiscovered side effects that potentially could be fatal, then how much do doctors really know about the brand-new chemicals they are prescribing?
Since epidemiologists, environmental toxicologists and molecular biologists have just begun to explore these questions through interdisciplinary research, yet undiscovered epigenetic effects from occupational or environmental exposures through the paternal germ line will undoubtedly be revealed in the future.
By setting a significance threshold, only variants in linkage disequilibrium (LD) with undiscovered mutations of moderate effect size are effectively considered in the enrichment or depletion analysis.
First, if parents are given permission to participate in the decision, then the matter to be decided (vaccinating or not) appears to them to be unimportant - this seems to be an important and so far undiscovered and unwanted side effect of psychological empowerment.
These corrections greatly reduce the power to detect true associations, which means that genetic variants with small or intermediate effects remain undiscovered.
However, it has been argued that intensive efforts to explain the genetic basis of quantitative traits by identifying underlying genes have yielded rather little (Travisano and Shaw 2013) and that genomic methods such as QTL analysis may leave important small-effect loci undiscovered (Rockman 2011; Travisano and Shaw 2013).
