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And the other part of the lesion in the testis consisted of undifferentiated blastemal tissue, abortive glomeruli and dysplastic tubules with intervening testicular tissue.
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Wilms' tumor (WT), or nephroblastoma, arises from metanephric blastemal cells that are unable to complete the mesenchymal epithelial transition (MET) resulting in a tumor with varying proportions of undifferentiated blastemal and stromal cells and primitive epithelial structures.
Our own previously published immuno-histochemical analysis of primary human WT sections, localized NCAM predominantly to the blastemal component indicating that an undifferentiated "blastemal cell" and NCAM+ cell might be interchangeable (Pode-Shakked et al, 2009; Roth et al, 1988a, b).
Occasionally, the nephrogenic blastema fails to mature into normal renal parenchyma, and the persistent blastemal tissue is then referred to as nephrogenic rests, which may undergo oncogenic mutation to form a malignant embryonal tumor known as nephroblastoma.
The relationship between undifferentiated tissues and differentiated tissues is relatively unexplored.
Undifferentiated connective tissue disease.
One of these co-morbidities is represented by undifferentiated connective tissue dysplasia (UCTD).
The purpose of this study was to evaluate pregnancy outcome in a cohort of patients with newly diagnosed undifferentiated connective tissue disease (UCTD).
I was diagnosed with retroperitoneal undifferentiated soft tissue sarcoma on December 17 , 2009when I was only 12 and a half years old.
Rhabdomyosarcoma arises from undifferentiated mesodermal tissue.
RA, rheumatoid arthritis; UCTD, undifferentiated connective tissue disease.
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