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PhenoVar filtered the search using a cut-off phenotypic match threshold to prevent undesired discovery of incidental findings and ranked the OMIM entries according to diagnostic score.
Moreover, through the optional use of a cut-off phenotypic weight threshold, the clinician can focus the analysis on the genetic causes which can potentially explain the specific phenotype/medical-issue at hand, thus preventing the undesired discovery of incidental findings.
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Drug/chemical discovery is a complex and time-consuming process that often leads to undesired side effects or toxicity [13].
In summary, several functional connections link in a complex network respiration, oncogenic signaling cascades, mGSK3, ROS levels and the PTP in tumor cells, making GSK-3 an appealing target for drug discovery, even if the pleiotropy of its functions exposes to the risk of undesired side effects.
"They are undesired people here.
Undesired appearance: perceptible browning, dryness, wilting.
The angst of being unloved, undesired, unattractive, unpopular, unsuccessful.
One can take it in heavy doses without any undesired effects.
Some are deliberately applied to bodies of water to destroy plants, insect larvae, or undesired fish.
The array of undesired noise plays a practical joke on traditional sensitivities.
Their message is that Erdoğan is an undesired player in active politics.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com