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Because the introduction of guinea pig mAbs in insulin immunoassays may reduce the amount of undesirable variables caused by the use of polyclonal antibodies, we sought to generate a guinea pig mAb against human insulin.
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We perform various robustness assessments by adding or dropping undesirable output variables.
This allows thresholds to be reverse engineered: by getting experts to identify sites as desirable and undesirable, field variables can subsequently be measured to derive the boundary between subjectively identified desirable and undesirable states.
Secondly, the variance of its computation time can be also large leading to undesirable highly variable decoding delays.
However, chimeric antibodies still generate undesirable anti-variable region response [8].
We identified several trade-offs (desirable outcomes for some variables, undesirable for others), involving most components of the study system.
Secondary outcome variable (undesirable outcome) was time when patient was lost to follow up, stopped or dropped out any of the five years follow up period.
This strategy of installing the guanidine group at this later stage was more successful in our hands as opposed to introducing the guanidine group early in the synthesis, the latter strategy gave us undesirable products and variable results.
As explained by Hayduk and Littvay (2012), "multiple indicators hamper theory by unnecessarily restricting the number of modeled latents" which is undesirable because "additional latent variables permit stronger statistical control of potential confounders, and encourage detailed investigation of mediating causal mechanisms" (p. 1).
Passive immunization is not always effective; the duration of immunity provided is brief and variable, and undesirable reactions may occur, especially if the antiserum is of nonhuman origin.
This unidirectional effect can sometimes lead to undesirable effects where a variable could cause the probability of high or low severity collision to increase at the cost of the other [38].
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