A large body of research has shown that black patients are less likely to get appropriate medications and surgeries than white ones are, regardless of their insurance or education level, and more likely to receive undesirable medical interventions, like amputations.
The justification being that no matter how desirable or undesirable such interventions will be for future generations, it is the future generations who will make the choice about which to convert into actual functionings.
Thus, at each iteration, we can directly compute the true stationary mass for undesirable states after intervention and make the decision about the control policy for the selected state as well.
The secondary outcomes will be the cost of the intervention, the incidence of vaccine-preventable diseases, the acceptability of the intervention, adverse events following immunisation and undesirable effects of the interventions.
In this article, optimization-based frameworks are introduced for elucidating the input-output structure of signaling networks and for pinpointing targeted disruptions leading to the silencing of undesirable outputs in therapeutic interventions.
The tools and indicators identified largely enable measurement of technical interventions and undesirable health (or pathological medical) outcomes.
The GRADE (Grade of Recommendation, Assessment, Development and Evaluation) system was used, with a strong recommendation indicating a clear advantage for an intervention and a weak recommendation indicating that the balance between desirable and undesirable effects of an intervention is not clearly defined.
Ron Bloom, a senior adviser to the task force, told the Senate banking committee that while the government's intervention was undesirable, it was also necessary to prevent "substantial job loss with a ripple effect throughout our entire economy".
HPA axis over-activation leading androgen excess would be undesirable in a therapeutic intervention designed to treat a chronic condition such as the metabolic syndrome.
