Sentence examples for undesirable cells from inspiring English sources

Apoptosis is an important continuous and highly regulated cellular process resulting in destruction of undesirable cells during development or homeostasis in multicellular organisms (Kaufmann and Hengartner 2011).

This involves the use of biochemistry to alter the expression of certain genetic sequences in human genotypes leading to the expression of desirable, or inhibition of undesirable, cells or human genes to improve athletic performance.

DOI: http://dx.doi.org/10.7554/eLife.08474.011 ATF4 is induced in a variety of stress conditions that arise in unhealthy, infected, and transformed cells; coupling these stress conditions to NKG2D ligand expression may enable destruction of undesirable cells.

When it is desired to apply this technique only to certain cells that exist in a heterogeneous tissue, surrounded by cells of other types such as connective tissue cells, it is essential to minimize the contribution of mRNA from undesirable cells by enriching the percentage of desirable cell types [ 5].

Our efforts to take advantage of natural cytotoxic anti-αGal antibodies as a means of destroying breast tumor cells, and to design a promoter specific for these undesirable cells, have to be considered as a preliminary contribution to the field of cancer gene therapy, given that our results have been obtained in cell line culture models.

Noise can lead to undesirable cell fate in cellular differentiation processes.

Cord blood expansion ex vivo can be achieved in liquid suspension through the addition of cytokines at the expense of often undesirable cell differentiation.

It remains to be seen whether prolonged FGF-2 secretion via rAAV may not lead to side (paracrine and autocrine) effects (activation of proliferation/differentiation of undesirable cell populations), even though we did not observe such problems when applying directly the current vector to focal experimental articular cartilage defects in vivo (Cucchiarini et al. 2005).

Unrepaired DNA lesions cause mutations, which can lead to undesirable cell death, carcinogenesis, or age-related pathophysiology.

While Fas is expressed by several tissues, the expression of FasL is tightly regulated at both transcriptional and post-transcriptional levels to avoid undesirable cell death.

All three conditions (and the spread of pathogenic fungi) are due to ectopic or otherwise undesirable cell growth, suggesting that the molecular target of rapamycin is a central controller of cell growth.