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G15, which is engaged in a GC base pair that closes the loop, underwent substantial change in H (5.8 → 9.7 ppm) but not N chemical shift (72.8 → 75.0 ppm) consistent with this site undergoing changes in chemical environment, but not chemical structure, upon Dox conjugation.
However, these within-domain patterns underwent substantial change when the whole dataset was modelled, indicating that domain-specific deficits can only be understood in relation to linked changes in domain-general processes.
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The 4q subtelomere therefore underwent substantial genomic changes during evolution, and its remodelling essentially involved D4Z4 and LINE sequences (see Fig. 2C).
Based on the aforementioned factors, in conjunction with their possession of characteristic traits of closed mitosis and spores that contain chitin and trehalose, as fungi do [ 8], microsporidia have been classified as the earliest diverging clade of sequenced fungi [ 9] that underwent substantial genetic changes during adaptive evolution.
One-third of patients underwent significant change in medical or surgical management based on hybrid imaging.
Daytime programming also underwent significant changes in the 1980s.
Yet, the gender gap shows huge variations and underwent significant changes during the 20th century.
"It will not bring any substantial change".
Did they engineer substantial change?
The remainder reported no substantial change.
Most did not register low fertility in the 1930s but underwent substantial declines in the 1950s after a short-lived baby boomlet.
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