"underwent significant changes" is correct and usable in written English.
It can be used when talking about something that has gone through a lot of transformation, either physical, emotional, or mental. For example: "The company underwent significant changes after their new CEO came on board."
Daytime programming also underwent significant changes in the 1980s.
Ironically, these are all members of the NHS scheme that only in 2008 underwent significant changes, increasing member contributions, capping employer contributions plus increasing retirement age to leave it on an even footing for the future.
The West Course was laid out by the architect Harry Colt in 1926 but underwent significant changes, at the behest of owner Richard Caring and overseen by Ernie Els, for last year's tournament.
Yet, the gender gap shows huge variations and underwent significant changes during the 20th century.
The remaining cells underwent significant changes in morphology: the original shape was gone, the cytoplasm became rougher, the nucleus showed pycnosis, and the refraction decreased, demonstrating obvious cellular damages.
Over the years, Yukon's political status underwent significant changes.
Reproductive cloning techniques underwent significant change in the 1990s, following the birth of Dolly, who was generated through the process of SCNT.
The north, or Nigerian Sudan, underwent significant change in the beginning of the 20th century, when a new economic pattern was created by the construction of a railroad that connected the region to the country's coastal ports.
The closing credits theme, "Captain Scarlet", underwent significant change after the completion of the first 14 episodes.
One-third of patients underwent significant change in medical or surgical management based on hybrid imaging.
Moreover, not only the cambial cells but also the developing tracheid cells underwent significant morphological changes.
