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The helicopter was one of many that underwent safety checks as a precaution on the advice of its operator Bond Air Services last July, but it was not withdrawn from service.
44 In Vellinga and colleagues' study, NA had been discontinued when cases of PML were observed and patients underwent safety MRI before the reintroduction on NA.
Prior to and after the study treatment, volunteers underwent safety clinical and laboratory screening.
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The NHS said the drug, which is being used to prevent some of the 1,000 deaths caused by cervical cancer each year, underwent "rigorous safety testing" before being chosen for the programme.
Patients were examined, questioned regarding adverse events and use of concomitant medications, and underwent routine safety laboratory testing periodically throughout the study.
Following an overnight fast, patients were given a placebo in a single-blind fashion QD and underwent baseline safety and pharmacodynamic assessments on Day 0 (pretreatment baseline) and received double-blind treatment with canagliflozin (25, 100, 200, or 400 mg QD) or placebo on Day 1 and Days 3 16.
Gatifloxacin underwent two "safety-related drug labeling changes" in 2001 and is the only quinolone that carries a "warning" about disturbances in glucose metabolism.
During the main treatment phase (weeks 0 12) patients underwent assessments for safety and tolerability at the end of each cycle.
… Ravens safeties Eric Weddle and Lardarius Webb both underwent concussion protocol in the fourth quarter but returned to play.
Many products remain on the market two or three decades, and these older products probably underwent far less stringent environmental and safety scrutiny then than they would today, analysts said.
We based these categories of contributing factors initially on a previously published framework of patient safety problems, 30 which underwent iterative modifications as new categories of factors were identified during our study.
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