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Then, the latter underwent conformational changes.
Upon auxin binding, Phe82 underwent conformational changes to accommodate the subsequent binding of Aux/IAA.
It is evident from the spectra that both Nter and Cter domains underwent conformational changes in presence of Ca2+.
We show that d-EAK16 also underwent conformational changes as a function of pH changes [Fig. 7].
Without the ligand, the Her3 subunit underwent conformational changes similar to those described above for the ligand-free EGFR subunit, including a bending of domain II.
Although the proapoptotic protein Bak and Bax underwent conformational changes after treatment (Fig. 3B and C; Fig. S2), the total level of proteins did not vary significantly (Fig. 4A).
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This result shows that mp53 underwent conformational change to wtp53.
Most interestingly, our computational simulations indicated two residues, Phe82 and Phe351, underwent significant conformational changes upon the sequential binding of auxin and Aux/IAA (such as Phe82 in Figure 8A).
Recently, the structure of bovine catalase was solved lacking the NADP cofactor (PDB ID: 3RGP) (Purwar et al., 2011), and in the NADP-free structure F197 underwent a conformational change as it no longer interacted with NADP.
In addition, the DNA molecule underwent two subtle but significant conformational changes during simulation.
Conformational changes were monitored by Raman spectroscopy.
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