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Nevertheless, we identified 33 pairs of highly polymorphic sites within a read length (36 bp) of one another and undertook a linkage survey of changes at these positions.
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We therefore undertook a record linkage study using Ontario health administrative data for FM graduates from U of T. The overall purpose of generating this information is to determine the type of information for physician resource planning that may come from tracking FM graduates using health administrative data.
We previously undertook a genome-wide linkage study and detected linkage between genetic markers on chromosome 7q32 and Gleason Grade (p = 0.0007).[ 9] This finding suggests that the 7q32 region might harbor genes for prostate cancer aggressiveness.
We undertook a genome-wide linkage analysis on 12 pedigree members, five of whom were classed as affected.
We undertook a bespoke patient-level linkage of clinical and administrative databases to study the effect of clinical exposures on long-term cardiovascular outcomes over many thousands of patient-years.
We have undertaken a record-linkage cohort study of cancer in people after cholecystectomy.
It is difficult to estimate the magnitude of these impacts without undertaking a comprehensive data linkage between jurisdictional workers' compensation and health datasets.
An international consortium undertaking a genome-wide linkage analysis in breast cancer families lacking BRCA1/ BRCA2 mutations identified one large family in which a complex pattern of inheritance of cancer susceptibility pointed to the hCHK2 gene on chromosome 22.
RK was the principal developer of the linkage strategy, undertook the data linkage and analysis and drafted the manuscript.
In order to assess the global functional significance of the hNCC gene list relative to a variety of other human cell and tissue types, we undertook average linkage hierarchical clustering of the gene lists, using SAGE transcriptome data from 14 other non-transformed samples.
However, data linkage is necessary to undertake a systematic analysis of the occurrence of person based disease from routine national statistics.
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